Author Archive

Possible antiproliferative action on tumor cells reported

Here we report the first clinical study aimed at assessing cannabinoid antitumoral action, specifically a pilot phase I trial in which nine patients with recurrent glioblastoma multiforme were administered THC intratumoraly.

 

British Journal of Cancer (2006) 95, 197–203. doi:10.1038/sj.bjc.6603236 www.bjcancer.com
Published online 27 June 2006

A pilot clinical study of Δ9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme

M Guzmán1, M J Duarte2, C Blázquez1, J Ravina2, M C Rosa2, I Galve-Roperh1, C Sánchez1, G Velasco1 and L González-Feria2

  1. 1Department of Biochemistry and Molecular Biology I, School of Biology, Complutense University, Madrid 28040, Spain
  2. 2Department of Neurosurgery, Hospital Universitario de Canarias, La Laguna, Tenerife 38320, Spain

Correspondence: Professor M Guzmán, E-mail: mgp@bbm1.ucm.es; Professor L González-Feria, E-mail: lgferia@yahoo.es

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Grape God by GrizzWeed

ggSTRAIN: Grape God
TYPE: hybrid
ORIGIN: Grapefruit/God bud
MEDIUM: Soil

LIGHTS: MH/HPS/T-8’S
NUTES: Private reserve, Family recipes
GROWER: GrizzWeed

APPEARANCE: hard, firm and dense
SMELL: Sweet, fruity and yet floral

BURN: Slow and even leaving a light grey to white ash at finish
topshelfsmokinsunsmTASTE: Distinctly sweet and fruity draw almost juicy. A robust flavor
EXHALE: mild light, excellent fruity aftertaste
HIGH: Quick come on with a heady buzz. That allows the user to stay happy and relaxed. Great as a AM or a PM smoke
MANICURE: High and tight but still leaving enough of the sugar leaves to add to the flavor.
OVERALL: An all around great smoke for either getting things done or for just a relaxing evening with friends

 

gg1-2015This is one of the top strains to be found in Alaska currently, The potent BC God crossed with the most excellent Grapefruit was a masterstroke and it is delightful to see this out in the hands of great horticulturists like GrizzWeed.

While GrizzWeed is a serious cultivator even in the hands of a novice first time grower I have been amazed at the yield and potency of this one.

http://www.facebook.com/grizzweed/ gw

 

Considering several encounters with this strain over the last year, each being a delightful surprise, and each encounter being with a different grower, I have decided that this is the best overall strain I have seen in 2015.

leafly.com/hybrid/grape-god

 

 

 

Start your engines…

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Alaska Microloan

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Rural Development Initiative Fund

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Final Adopted Regulations

As of 12/1/2015 Regulation of Marijuana Industry
.

Where did cannabis come from?

Cannabis came to the Middle East between 2000 B.C. and 1400 B.C., and it was probably used there by the Scythians, a nomadic Indo-European group…Germanic tribes brought the drug into Germany, and marijuana went from there to Britain during the 5th century with the Anglo-Saxon invasions. Over the next centuries, cannabis migrated to various regions of the world, traveling through Africa, reaching South America in the 19th century and being carried north afterwards, eventually reaching North America.

http://www.livescience.com/48337-marijuana-history-how-cannabis-travelled-world.html

Final Adopted Regulations as of 12/1/2015

https://www.commerce.alaska.gov/web/Portals/9/pub/FinalRegsThrough12-1-15.pdf

Kosher Kush Review

Strain: Kosher Kush

Type: Indica

Origin: DNA’s Reserva Privada seed line, Kosher Kush won the High Times Indica Cup in 2010 and 2011.

Medium: Hydro

Lighting: LED

Nutes: Classified

Grower: NLCC

Appearance: Tight and very sparkly.

Smell: Sharp Pine tones

Burn: Very clean

Taste: Baby, I promise I won’t…na, here it comes, you ready? Rich and full flavored, let’s you know it is going to be at work for a while.

Exhale: Yea, about that work thing, you should be able to tell by now that this is going to be an A ticket ride.

Hkosherkush-dec2015igh: “Hello, I’m Kosher K, I’m just going to move into this corner of your head over here and play with the signal to noise for a while, yea, this wire can go over here, and this one…Oh, your still here? Go get a Pizza or something.”

Manicure: Excellent

Overall: I am savoring every puff of this first rate strain. I know it will be gone all to soon and I’ll only have memories that I can’t remember because this is some really fucking good weed. Very good pain relief, I can still sort of feel it, I just don’t feel it as an urgent thing…it’s more like I casually remember it is still there waiting for the medicine to wear off. But this has some serious staying power and a night of moderate (OK, my moderate might not match YOUR moderate, 4 joints, thin ones) smoking had me awaken with a very nice afterbuzz and feeling well rested.

This top shelf private reserve quality hydro I’m going to be following eagerly.


S20151204_0002 S20151204_0003 S20151204_0004 S20151204_0005

Purple Kush from NLCC/Medical Seeds

Medical Marijuana
pk1STRAIN: Purple Kush
TYPE: Indica
ORIGIN: Medical Seeds
MEDIUM: Hydro under LED
NUTES: CLASSIFIED
GROWER: NLCC
APPEARANCE: Sparkly and tight, not rocks but certainly not fluffly nugs either.
SMELL: Musty dankness, a good but not bold smell
BURN: Clean
TASTE: As to be expected from a PK, rich and flavorful.
EXHALE: Terpines lingering on the tongue, resiny
HIGH: 4 tokes in and I am suspecting a creeper. 8 Pm and my first toke of the day. Pain subsiding under a slow cresting wave, not a head rusher but a solid body stone and a pleasant head buzz setting in.
MANICURE: Tight , not excessive, just enough guard left to hold trichs.
OVERALL: Quite like the Purple Kush that has been my mainstay for the last decade, solid performer, looking forward to some rosin later tonight, I’ll try and remember to post pics. 8.3 Overall

topshelf

pk-01-dec pk-o2-dec

 


Strain Reports on Alaska Hemp (http://alaskahemp.com/420/category/alaska-hemp/strains/)


Avidekel, Cannabidiol of 16% Patent


 

United States Patent Application 20140259228
Kind Code A1
Cohen; Ytzchak September 11, 2014

CANNABIS PLANT NAMED ‘AVIDEKEL’

Abstract
The disclosure relates to a new and distinct cultivar of Cannabis Sativa plant named `Avidekel`, characterized by a high amount of Cannabidiol (CBD) (16.3%) and a very low amount of Tetrahydrocannabinol (THC, 0.8%).


Inventors: Cohen; Ytzchak; (Tel Aviv, IL)
Applicant:
Name City State Country Type

Cohen; Ytzchak
Tel Aviv IL
Family ID: 1000000548761
Appl. No.: 14/193252
Filed: February 28, 2014


Related U.S. Patent Documents

Application Number Filing Date Patent Number
61768567 Feb 25, 2013

Current U.S. Class: 800/298
Current CPC Class: A01H 5/02 20130101
Class at Publication: 800/298
International Class: A01H 5/02 20060101 A01H005/02

Claims


1. A new and distinct Cannabis Sativa L. ssp. indica plant named Avidekel, characterized by a high amount of Cannabidiol of greater than approximately 16% and a very low amount of THC of less than 1%, as illustrated and described herein.


Description


BACKGROUND

[0001] The disclosure is directed to a new and distinct cultivar of Cannabis Sativa plant named `Avidekel`, characterized by a high amount of Cannabidiol (CBD) (16.3%) and a very low amount of Tetrahydrocannabinol (THC, 0.8%).

SUMMARY

[0002] Provided herein is a new and distinct Cannabis Sativa L. ssp. indica plant named Avidekel, characterized by a high amount of Cannabidiol (CBD) of greater than approximately 16% and a very low amount of Tetrahydrocannabinol (THC) of less than 1%, as illustrated and described herein.

BRIEF DESCRIPTION OF THE DRAWINGS

[0003] FIG. 1 illustrates a single fully grown plant of the variety;

[0004] FIG. 2 illustrates a single leaf of the variety;

[0005] FIG. 3 illustrates a flowering plant in close-up; and

[0006] FIG. 4 illustrates a dried bud.

DESCRIPTION

[0007] This invention relates to a new hybrid marijuana plant, Cannabis sativa L. ssp. indica named Avidekel. The Avidekel is a medicinal variety of marijuana notable for a high amount of Cannabidiol (CBD) (16.3%) and a very low amount of THC (0.8%).

[0008] The present plant was developed over 3 years through selective breeding from parents of unknown provenance in Birya, Israel. Generally production occurs through asexual propagation using stem cuttings. The plant may be grown outside in a normal warm summer, including many locations below 50N and virtually all climates below 45N.

Plant

[0009] Exposed Plant Structure

[0010] The Plant is an annual, dioecious plant with bush-like stature. The natural height at 5 months old of indoor growth is .about.130 cm. A detailed list of characteristics follows: [0011] Botanical classification: Cannabis sativa L. ssp. indica [0012] Parentage unknown [0013] Propagation: Stem cuttings. [0014] Time to initiate roots in summer: [0015] Plant description: annual, dioecious flowering shrub; multi-stemmed; freely branching; removal of the terminal bud enhances lateral branch development. [0016] Root description: Short taproot (less than 30 cm). Medium to fine, dense lateral roots; white in color, brownish when “potbound” (rootbound).

[0017] First Year Stems: [0018] Shape–round. Fine pubescence. [0019] First year stem color–young stem: 144C older stems: 144A (The Royal Horticultural Society Colour Chart), [0020] First year stem diameter is 4.5 cm. [0021] First year trunk diameter is 7.5 cm at the soil line. [0022] Stem Strength–lateral stems are strong but benefit from being staked during flowering. [0023] Internodes’ length.–6 cm in the lower half and 4 cm in the upper half.

[0024] Foliage Description: [0025] Branch strength–strong. [0026] Branch description–branches are short, densely branched with short, broad leaflets. [0027] Leaf Arrangement–palmately compound (digitate) leaves with 7 leaflets on big fan leaves and 5 on small fan leaves per leaf. [0028] Texture (upper and lower surfaces). Upper surface scabrid with non-visible stiff hairs; lower surface more or less densely pubescent, covered with sessile glands. [0029] Venation pattern–Palmately Compound (Digitate), with serrated leaflets. Each serration has a lateral vein extending to its tip from the central (primary) vein of the leaflet. From each lateral vein there is usually a single spur vein (sublateral vein) extending to the notch of each serration. [0030] Color of emerging foliage (upper surface). A cross between 144A and 144C (The Royal Horticultural Society Colour Chart, 1995 Edition.) [0031] Petiole length–Average length of petiole of fan leaves 7 cm. More than 30% of the petioles are purple.

[0032] Vegetative Bud Description: [0033] Dried flower buds are deep dark green and highly resinous. Fragrance is weaker than similar varieties, having an earthy medicinal berry smell.

[0034] Flower Description: [0035] Inflorescence is cone–or head-like, dense cluster of false spikes with solitary flowers instead of cymes. Enclosed by glandular, beaked bracteole. Calyxes are densely covered with trichomes; Flowers are often paired. Petals are absent. [0036] Spike length–ranges between 5 cm and 3 cm; [0037] Pistils description–white, few, short, brown at maturation. [0038] Dried flower colour–Dried flower buds are a deep, dark green. [0039] Flower size–about 1 cm in diameter and about 1.1 cm in height. [0040] Flowering time–8 weeks

[0041] Peduncles: [0042] Strength: Strong, but can bend horizontally from weight of flower buds. [0043] Texture: Moderately smooth, glabrous. [0044] Pedicels description: Short, scabrid with sessile glands and visible hairs.

[0045] Seeds may be acquired through STS breeding. This involves inducing a female plant to become a male plant by altering its hormones using (in this case) silver nitrate and sodium thiosulfate. The male plant may then be used to pollinate a female of the same variety and collect the seeds. The relative proportion of male plants is low/medium.

[0046] The plant variety is similar to the Erez, also a Cannabis indica subspecies.

[0047] The inflorescence contains a high amount of Cannabidiol (CBD) (16.3%) and a very low amount of THC (0.8%). This enables patients to obtain the medicinal benefits of CBD, without the psychoactive effects of THC.

[0048] This plant has strong anti-inflammatory properties. It can be used to treat a wide range of health disorders and diseases involving inflammation, as well as sleep disorders and digestive orders.

[0049] Prefers `soft water`; consider filtering the tap water if it has an EC higher than 0.6

[0050] Light was provided at a power of 600 W HPS; plant distance from light was 100-120 cm.

TABLE-US-00001 USDA Plants Growth Habit Code FB Vigor 4.5/5 Productivity Good – 500 g/m2 indoor, 250-400 g/plant outdoor Male flowering timing average Flowering score 7.5 Branches strong Fruit bloated THC level 0.8% CBD level 16.3%

[0051] A crop was grown having the following times of growth cycle operations:

TABLE-US-00002 date of cutting/or from seeding 21 Apr. 2011 date transferred to cones pot of 0.8 liter 27 Apr. 2011 Date of moved to pot of 11 liters 23 May 2011 Date of taking clones 03 Jun. 2011 Date – start to flower 27 Jun. 2011 Ending flowering 23 Aug. 2011 wet flowers (grams) 524 wet leaves (grams) 250 wet branches (grams) 230.2 dry flowers (grams) 132.6 Mothers 1-1.5 meter Pot size 25 L

[0052] Permits are required for growth of medical marijuana in certain states in the US and Israel.

The Cannabis Kitchen Cookbook: Feel-Good Food for Home Cooks

cccAn Upscale Cookbook for Enthusiasts of All Skill Levels That Approaches Cannabis as an Ingredient to Explore

Cannabis is one of the hottest ingredients to hit the culinary world, and cannabis-infused food is an evolving art and science. In The Cannabis Kitchen Cookbook, chefs in the know from Amherst to Anaheim share their secrets for infusing everything from oil and agave to soups and cocktails with this once taboo ingredient.

Covering every meal from brunch to late-night cocktails and snacks, The Cannabis Kitchen Cookbook approaches cannabis as yet another fine ingredient to be studied and savored, like a great wine, a premium cigar, gourmet chocolate, or single malt scotch. With more than one hundred fully tested recipes from experienced professional chefs, The Cannabis Kitchen Cookbook guides readers through the process of making fresh, tasty, and healthy home-cooked meals using cannabis as the main additive.

The cookbook also provides step-by-step instructions on preparing cannabis for use in the kitchen as well as advice on personalizing dosage for different tastes. Tips for trimming, processing, storing, and preserving cannabis are included along with a “buyer’s guide” that sheds light on the many varieties of cannabis flavor profiles, showcasing strains based not only on feel-good levels, but more importantly, taste-good levels

Contributors to this Collection include . . .
Leslie Cerier • Mike DeLao • Scott Durrah • Joey Galeano • Rowan Lehrman • Andie Leon • Catjia Redfern • Herb Seidel • Donna Shields • Grace Gutierrez • Lucienne Bercow Lazarus • Emily Sloat • Rabib Rafiq • Chris Kilham

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